概念.減重橋接


在2011年3月的哈佛健康部落格(Harvard Health Blog)裡,Julie Corliss提出了「縮小行為意願之間的差距使體重減輕並維持(Bridge the intention-behavior gap to lose weight and keep it off)」。大部分減重的人都知道哪些東西該吃,哪些東西該避免。然而,也會有像她朋友這樣:「我知道我不應該吃掉整袋軟糖焦糖爆米花,但它真的太美味了」


Stay up past midnight watching TV Record TV show to watch earlier on another night
Trouble falling asleep. Woke up late, skipped breakfast Use relaxation techniques to fall asleep
Didn’t pack lunch, went to fast-food restaurant Pack your lunch the night before
Stressed at work. Raided candy bowl by reception desk Keep healthy snacks at work (100-calorie cracker snack packs, fresh fruit)
Felt discouraged skipped going to gym Plan in advance to meet a friend or trainer at gym

將意願與行為去做橋接,是減重最為關鍵的步驟。
因此,本院提供減重橋接(Lose Weight Bridge)。



減重橋接(Lose Weight Bridge)
四個月的療程過程中,幫助減重者能順利地將意願與行為做橋接及改善,進一步達到長期體重維持的目標。

本院減重特診就診流程
1. 掛號
2. 測量血壓/心跳/身高/體重/抽血檢驗
3. Inbody量測當下身體組成
4. 醫師問診(了解減重原因、目標體重、飲食衛教、運動鼓勵及Line@提醒)
5. 選擇減重橋接方式(初診)
a.胃內肉毒施作(intragastric botulinum toxin injection)、瑞貝適(Rybelsus®)口服藥或康纖芙(Contrave®)口服藥善纖達針劑(Saxenda®)瘦瘦筆或(三擇一)、執行全腹部超音波或甲狀腺超音波檢查(二擇一)
b.善纖達針劑(Saxenda®)瘦瘦筆、執行甲狀腺超音波檢查
6. 批價
7. 藥師調劑說明
8. 護理師說明口服藥或針劑的注意事項

實證醫學證據(Evidence Based)
1. 使用胃內肉毒施作合併飲食控制,63.2%參與者體重下降超過10%,95.9%參與者體重下降超過5%。Hsu PK, Wu CL, Yang YH, Wei JC. Effect of Intragastric Botulinum Type A Injection Combined with a Low-Calorie High-Protein Diet in Adults with Overweight or Obesity. J Clin Med. 2022 Jun 10;11(12):3325. doi: 10.3390/jcm11123325. PMID: 35743396; PMCID: PMC9225463.

2. 胃內肉毒注射對於肥胖治療是有效果的,在適當的劑量,多處胃部注射區域,合併飲食控制至關重要。Yen YA, Wang CC, Sung WW, Fang KC, Huang SM, Lin CC, Tsai MC, Yang TW. Intragastric injection of botulinum toxin A for weight loss: A systematic review and meta-analysis of randomized controlled trials. J Gastroenterol Hepatol. 2022 Jun;37(6):983-992. doi: 10.1111/jgh.15847. Epub 2022 Apr 22. PMID: 35383416.

3. 使用胃內肉毒注射3個月後,體重平均下降達7.77%;使用胃內肉毒注射合併Liraglutide(善纖達)3個月後,體重平均下降達16.78%;使用胃內肉毒注射6個月後,體重平均下降達10.02%;使用胃內肉毒注射合併Liraglutide(善纖達)6個月後,體重平均下降達24.88%。Altunal, Çetin, et al. "Intragastric injection botulinum toxin A for obesity management with or without liraglutide." European Review for Medical and Pharmacological Sciences (2023).

4. 使用康纖芙16週後,45.8%參與者體重下降超過5%,11.9%參與者體重下降超過10%。le Roux CW, Fils-Aimé N, Camacho F, Gould E, Barakat M. The relationship between early weight loss and weight loss maintenance with naltrexone-bupropion therapy. EClinicalMedicine. 2022 May 27;49:101436. doi: 10.1016/j.eclinm.2022.101436. PMID: 35747175; PMCID: PMC9156890.

5. 糖尿病患者在使用瑞貝適26週後,平均降低體重2.3公斤(7mg)和3.7公斤(14mg)。Rybelsus (semaglutide). Updated 12/2022. 

6. 使用善纖達最大劑量持續3個月,53.7%參與體重下降超過5%,14.9%參與者體重下降超過10%:使用善纖達最大劑量持續6個月,87.3%參與者體重下降超過5%,54.9%參與者體重下降超過10%,23.5%參與者體重下降超過15%。Ghusn W, De la Rosa A, Sacoto D, et al. Weight Loss Outcomes Associated With Semaglutide Treatment for Patients With Overweight or Obesity. JAMA NetwOpen. 2022;5(9):e2231982. doi:10.1001/jamanetworkopen.2022.31982